. Author manuscript; available in PMC: 2016 May 1.

Published in final edited form as: J Pediatr. 2015 Mar 11;166(5):1152–1157.e6. doi: 10.1016/j.jpeds.2015.01.044

Table 5.

Covariate adjustment for association of rs7512462 with NBS IRT in the French sample (n = 80).

Covariate in Model	p_SNP	β_SNP (95% CI)	p_covariate	R² model
None (rs7512462 only)	0.76	3 (−18, 24)	NA	0.00
Sex	0.78	3 (−18, 24)	0.35	0.01
CFTR^a	0.72	4 (−18, 25)	0.58	0.01
IRT assay	0.67	5 (−17, 26)	0.38	0.02
Meconium ileus^b	0.83	3 (−20, 25)	0.33	0.01
Principal components^c	0.83	2 (−19, 24)	0.64	0.06

: Subjects are classified as delF508 homozygotes versus all other mutations.

: Based on a total sample of 140; 8 subjects are missing Meconium ileus status.

: Adjusted for population structure, based on the first four principal components.