Table 2.
Adjusted Geometric Mean Concentrations of Environmental Phenols in NCS Pregnant Women
| Analyte (μg/L)
|
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BP-3 | BPA | TCS | MP | PP | 2,4-DCP | 2,5-DCP | |||||||||
|
| |||||||||||||||
| Category | N | Mean (95% CI) |
P-value | Mean (95% CI) |
P-value | Mean (95% CI) |
P-value | Mean (95% CI) |
P-value | Mean (95% CI) |
P-value | Mean (95% CI) |
P-value | Mean (95% CI) |
P-value |
| All Females | 506 | 59.5 (49.7,71.3) | 1.4 (1.2,1.5) | 19.0 (16.1,22.4) | 103.5 (91.4,117.2) | 19.1 (16.1,22.6) | 0.70 (0.61,0.80) | 3.9 (3.3,4.8) | |||||||
|
| |||||||||||||||
| Study Site | 0.02 | 0.42 | 0.2 | 0.01 | 0.03 | <0.0001 | <0.0001 | ||||||||
|
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| Age (yrs) | 0.08 | 0.06 | 0.07 | 0.21 | 0.64 | 0.11 | 0.52 | ||||||||
|
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| 16–29 | 263 | ||||||||||||||
| 30–44 | 243 | ||||||||||||||
|
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| Race/ethnicity | 0.02 | 0.12 | 0.04 | 0.07 | 0.42 | <0.0001 | <0.0001 | ||||||||
|
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| Non-Hispanic black | 30 | 23.0 (10.8,48.7) | 14.2 (6.9,29.2) | 1.68 (1.12,2.51) | 18.8 (10.3,34.2) | ||||||||||
| Non-Hispanic white | 328 | 72.0 (57.0,90.9) | 16.4 (13.1,20.5) | 0.55 (0.48,0.62) | 2.5 (2.1,3.1) | ||||||||||
| Hispanic | 99 | 54.0 (33.9,86.2) | 33.9 (21.7,63.0) | 1.14 (0.89,1.46) | 9.0 (6.2,13.0) | ||||||||||
| Other | 49 | 36.2 (20.4,64.2) | 18.8 (10.9,32.5) | 0.74 (0.54,1.0) | 5.3 (3.4,8.4) | ||||||||||
|
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| Education | 0.02 | 0.77 | 0.04 | 0.06 | 0.04 | 0.08 | 0.04 | ||||||||
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| Income | 0.38 | 0.47 | 0.29 | 0.8 | 0.15 | 0.77 | 0.48 | ||||||||
| Urine creatinine | <0.0001 | <0.0001 | <0.0001 | <0.0001 | <0.0001 | <0.0001 | <0.0001 | ||||||||
Overall geometric means are presented for All Females. Adjusted geometric means are shown for subgroups when race/ethnicity was significant (p<0.05) in the regression analysis, using the covariates study site, age, race/ethnicity, education, income, and log urinary creatinine. Study site was frequently significant, but age was not for any of the urine phenol results.
Detection frequencies were benzophenone-3 (BP-3) 100%, BPA 89.1%, triclosan (TCS) 81%, Methyl paraben (MP) 100%, Propyl paraben (PP) 98.4%, 2,4-dichlorophenol (2,4-DCP) 82.8%, and 2,5-dichlorophenol (2,5-DCP) 94.1%.