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. 2015 Aug 10;10(8):e0135496. doi: 10.1371/journal.pone.0135496

Table 2. In vitro contracture test status, 2004–2010 cohort.

in vitro contracture test p-value
MHN MHS a
Number of subjects (%) 247 (54.4%) 207 (45.6%)
Demographic data
 Age (mean±sd) 25.8±5.2 25.8±5.4 0.96
 Sex ratio (M/F) 225/22 199/8 0.04
Circumstances 0.58
 Cross country 11 13
 Running + jacket 133 111
 Running + load 53 36
 Other 19 19
Clinical data
 Temperature 40.1±0.9°C 40.0±1°C 0.43
 Coma 130 (53.1%) 115 (46.9%) 0.81
 Seizures 11 (64.7%) 6 (35.3%) 0.68
 Confusion 111 (53.1%) 98 (46.9%) 0.61
Biological data
 Renal failure 34 (50.7%) 33 (49.3%) 0.90
 Hepatic failure 21 (46.7%) 24 (53.3%) 0.56

Legend: MHN, malignant hyperthermia normal response; MHS, malignant hyperthermia susceptible.

aIncluding MHS for caffeine and MHS for halothane patients.