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. 2015 Aug 10;10(8):e0134876. doi: 10.1371/journal.pone.0134876

Fig 3. Telokin phosphorylation in gastric fundus smooth muscles pre-contracted with 1μM CCh is increased by compounds that elevate cGMP.

Fig 3

A. Representative recordings of the contractile response to 1μM CCh, and the relaxation responses evoked by 50μM 8Br-cGMP (n = 6) or 10μM SNP (n = 6) in the presence of 1μM CCh. Average ratios ± SD of pS13:telokin, pT38:CPI-17, pT696: MYPT1, pT853:MYPT1, and pS19:MLC and representative western blots of the phosphorylation of (B) telokin S13, (C) CPI-17 T38, (D) MYPT1 T696 and T853, and (E) MLC S19 evoked by 50μM 8Br-cGMP (n = 6) or 10μM SNP (n = 6) in the presence of 30mM KCl. *P<0.01, # P<0.05, compared to untreated controls. ‡ P<0.05 compared to 1μM CCh treated muscles.