Table 2.

Functional annotation cluster analyses of genes^* showing significant^§ differences in DNA methylation by sex

Comparison	Cluster	No. of Genes	Enrichment Score†
Males vs. Females without PTSD	Membrane	247	2.27
	Lipoprotein	43	2.21
	Regulation of hormone secretion	27	2.1
Males vs Females with PTSD	Wnt signaling pathway	13	1.18
	Membrane	191	1.16
	Neurological system process	46	0.88

^*All genes are identified in terms of DAVID IDs ^[67]; genes can appear in more than one cluster.

^§Defined as p<0.05.

^†Defined as the geometric mean of the annotation cluster p values, in negative log scale.