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. Author manuscript; available in PMC: 2015 Aug 10.
Published in final edited form as: J Pharmacol Sci. 2014 Apr 19;125(1):6–38. doi: 10.1254/jphs.13r04cr

Figure 4.

Figure 4

The Maltsev-Lakatta model (10) predicts the wide range of pacemaker rate modulation via variations in SR Ca2+ pumping rate (1 to 30 mM/s), mimicking various degrees of PKA-dependent phospholamban phosphorylation. Modified from (10).