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. 2015 Aug 9;14(Suppl 2):235–245. doi: 10.4137/CIN.S17286

Table 3.

The description of HMPL Part II (Parse.HMPL.pl) output files.

FILE NAME CONTENTS
*.grX
eg, MCF10A.gr5
The CpG sites with coverage greater than X (X > 0).
*.all.HM.sites
eg, MCF10A.gr5.all.HM.sites
The hemimethylated CpG sites identified by the high and low cutoff values.
*.all.HM.sites.annotated
eg, MCF10A.gr5.all.HM.sites.annotated
The annotated hemimethylated sites (ie, gene names are provided).
*.all.labelled.CG
eg, MCF10A.gr5.all.labelled.CG
The CpG sites with coverage greater than X and with the labels of methylation states (P: partially methylated, M: methylated, U: unmethylated).
*. Summary
eg, MCF10A.gr5.summary
The summary file for all the methylation states of single hemimethylation sites and clusters.
*.all.HMClusters
eg, MCF10A.gr5.all.HM.Clusters
All hemimethylated clusters.
*.all.Rev.Clusters
eg, MCF10A.gr5.all.Rev.Clusters
All of the polarity (or reverse) clusters, including both consecutive and non-consecutive polarity clusters.
*.non.Rev.Clusters
eg, MCF10A.gr5.non.Rev.Clusters
The hemimethylated clusters that are not polarity patterns.
*.Singleton
eg, MCF10A.gr5.Singleton
Single hemimethylated CpG sites.
*.consec.revs.Clusters
eg, MCF10A.gr5.consec.revs.Clusters
The consecutive polarity (or reverse) clusters (ie, with just two consecutive CpG sites).
*.non.consec.revs.Clusters
eg, MCF10A.gr5.non.consec.revs.Clusters
The non-consecutive polarity clusters (ie, with two CpG sites that are not consecutive).
*.compare
eg, MM.gr5.all.HM.sites.annotated.compare
MM.gr5.consec.revs.Clusters.compare
MM.gr5.non.consec.revs.Clusters.compare
MM.non.Rev.Clusters.compare
MM.gr5.Singleton.compare
The results of comparing two samples.
(Note: To save space, we use “MM” to denote “MCF10A.MCF7” for the file names in the left column).