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Longitudinal DNA methylation (DNAm) modifications of DNA methyltransferase (DNMT) loci in response to trauma in posttraumatic stress disorder (PTSD) cases and trauma-exposed controls. DNMT3B (region) represents the mean of 12 CpG sites. Differences between PTSD cases and trauma-exposed controls were tested by paired-sample t-tests (N = 60; 30 PTSD cases and 30 matched controls). Error bars represent standard error of the mean. *: p<0.05; **:p<0.01; ***:p<0.001.
