Table 3.
Classification of GVHD | ATG group (n=24) | FLU group (n=32) | P value |
---|---|---|---|
aGVHD within 100 days (n,%) | 4 (16.7) | 16 (50.0)* | 0.018 |
Grade 1–2 | 4 (16.7) | 10 (31.25) | |
Grade 3–4 | 0 (0.0) | 6 (18.75) | |
GVHD post 100 d (n, %) | |||
aGVHD | 8 (33.3) | 10 (31.2) | 0.969 |
cGVHD | 12 (50) | 8 (25) | 0.274 |
Mild | 4 | 3 | |
Moderate | 4 | 3 | |
Severe | 4 | 2 | |
Classic cGVHD | 6 (25.0) | 4 (12.5) | 0.298 |
Overlap GVHD | 6 (25.0) | 4 (12.5) | 0.298 |
Extensive cGVHD (n,%) | 9 (37.5) | 3 (9.4)* | 0.019 |
Oral GVHD complications post 100 d (n,%) | 3 (12.5) | 14 (43.8)* | 0.018 |
Sever infection# | 12 (50.0) | 8 (25.0)* | 0.024 |
Liver dysfunction | 10 (41.7) | 22 (68.8) | 0.058 |
Elevated bilirubin | 12 (50.0) | 6 (18.8)* | 0.021 |
PTLD | 2 (8.3) | 1 (3.1) | 0.565 |
GVHD – graft-versus-host disease; cGVHD – chronic GVHD; aGVGD – acute GVHD; PTLD – post transplant lymphoproliferative disease. Note: In comparison to ATG group,
P<0.05.
Sever infection including pulmonary aspergillosis, interstitial pneumonia, cytomegalovirus infection or sepsis.