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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Curr Pharmacol Rep. 2015 Feb 18;1(4):272–282. doi: 10.1007/s40495-015-0024-z

Table 2.

Inhibitory activity of ITCs against BC cells in vitro and in vivo

ITC and vegetable
derivatives of ITC		 BC cell lines/ BC animal models Reference
No.
AITC,
AITC-rich mustard
seed powder,
NAC-AITC,
AITC & Celecoxib		 Cell lines: UM-UC-3, T24, AY-27 [69, 81–83]
Rats: Orthotopic AY-27 BC model,
subcutaneous AY-27 BC model		 [32, 84, 85,
91]
BITC Cell lines: UM-UC-3, T24 [69, 82, 83]
Rats: Orthotopic BBN-induced BC
model		 [90]
PEITC Cell lines: UM-UC-3, T24 [69, 82, 83]
SF, SF-rich broccoli
sprout extracts, ECN		 Cell lines: UM-UC-3, T24, RT4, J82, UM-UC-3,
Normal human urothelial cells, 5637		 [69, 82, 83,
95, 96, 101]
Rats: Orthotopic BBN-induced BC
model		 [67]
Mice: Subcutaneous UM-UC-3 xenograft
model		 [31, 86]