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. 2015 Aug 5;10:5049–5057. doi: 10.2147/IJN.S84565

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© 2015 Xue et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Oil Red O staining in the liver.

Notes: (A) Control group (100×); (B) BBR (100 mg/kg) (100×); (C) BBR-SLNs (100 mg/kg) (100×); (D) BBR-SLNs (50 mg/kg) (100×); and (E) The red area coefficient with different groups. Oil Red O staining. **P<0.01 versus the control group; ^##P<0.01 versus the BBR group.

Abbreviations: BBR, berberine; BBR-SLNs-H, berberine solid lipid nanoparticles high-dose group; BBR-SLNs-L, berberine solid lipid nanoparticles low-dose group; SLNs, solid lipid nanoparticles.

Oil Red O staining in the liver.

Notes: (A) Control group (100×); (B) BBR (100 mg/kg) (100×); (C) BBR-SLNs (100 mg/kg) (100×); (D) BBR-SLNs (50 mg/kg) (100×); and (E) The red area coefficient with different groups. Oil Red O staining. **P<0.01 versus the control group; ^##P<0.01 versus the BBR group.

Abbreviations: BBR, berberine; BBR-SLNs-H, berberine solid lipid nanoparticles high-dose group; BBR-SLNs-L, berberine solid lipid nanoparticles low-dose group; SLNs, solid lipid nanoparticles.