Table 1.
Baseline characteristics comparing intervention versus control.
| Characteristics | Intervention (n = 24) | Control (n = 26) | P value | Reference range |
|---|---|---|---|---|
| Age (years) | 53.8 (10.0) | 56.5 (8.1) | 0.28 | |
| CAG repeat length | 47.3 (4.9) | 46.9 (2.7) | 0.68 | <39 |
| CK (U/L) | 1038 (616) | 1232 (1171) | 0.47 | 52–386 |
| IGF1 (ng/mL) | 137.8 (51.1) | 155.3 (39.5) | 0.18 | 87–283 |
| Testosterone, total (ng/dL) | 385.2 (109.6) | 382.4 (153.9) | 0.94 | 181–758 |
| Disease duration (years) | 15.1 (7.5) | 16.0 (10.7) | 0.11 | |
| Bulbar Rating Scale | 92.3 (4.1) | 92.3 (4.7) | 0.99 | |
| Body mass index | 28.2 (5.1) | 28.3 (10.7) | 0.61 | |
| QMA total strength (% predicted) | 41.0 (16.9) | 39.3 (20.8) | 0.68 | |
| QMA UE strength | 40.0 (16.0) | 36.0 (20.0) | 0.97 | |
| QMA LE strength | 41.7 (17.6) | 41.9 (21.3) | 0.41 |
Data are given as mean (SD). CAG, cytosine adenine guanine; CK, creatine kinase; IGF-1, insulin-like growth factor 1; QMA, quantitative muscle assessment; UE, upper extremity; LE, lower extremity.