Table III.

Univariable and Multivariable Logistic Regression Models for Anemia (Hemoglobin < 13 g/dL for men; Hemoglobin < 12 g/dL for women)

Variable1	Univariable Models			Multivariable Model2
	Parameter estimate (SE)	OR (95% CI)	P	Parameter estimate (SE)2	aOR (95% CI)	P
Age, year	4.13x10−2 (2.61x10−2)	1.042 (0.99–1.097)	0.11	6x10−2 (3.03x10−2)	1.062 (1.001–1.127)	<0.05
Sex, 1=male	−1.31 (0.51)	0.27 (0.1–0.727)	<0.01
Race, 1=Caucasian	−2.24 (1.04)	0.107 (0.014–0.823)	0.03	−2.48 (1.08)	0.084 (0.01–0.693)	0.02
Hepatitis C, 1=yes	0.84 (0.72)	2.314 (0.569–9.402)	0.24
Platelet Count, x109/L	9.91x10−3 (3.50x10−3)	1.01 (1.003–1.017)	<0.01	1.19x10−2 (4.31x10−3)	1.012 (1.003–1.021)	<0.01
Total Monocyte Cell Count, cells3	−1x10−5 (2x10−5)	1 (1-1)	0.53
CD14dimCD16+ Cell Count, cells	2.27x10−4 (1.44x10−4)	1 (1–1.001)	0.11
sCD163, ng/mL	1.06x10−3 (5.66x10−4)	1.001 (1–1.002)	0.06
IL-6, pg/mL	2.78x10−2 (1.83x10−2)	1.028 (0.992–1.066)	0.13

¹All variables with p<0.25 in univariable analysis are shown in the table. Variables tested but not shown include: smoking status, body mass index, lean body mass, _eGFR_cr, creatinine, protease inhibitor status, thymidine analogue status, HIV-1 RNA <50 copies/mL, HIV-1 RNA level (as continuous variable), current and nadir CD4⁺ T cell count, HIV duration, ART duration, white blood cell count, %CD14⁺CD16⁺, CD14⁺CD16⁺ cell count, %CD14^dimCD16⁺, sCD14, IP-10, %CD4⁺DR⁺38⁺, %CD8⁺DR⁺38⁺, hsCRP, sTNF-RI, sTNF-RII.

²All variables with p<0.25 in univariable analysis were considered in the final model selection. Backward elimination was used for final model selection.

³Total monocyte count included in all models including CD4^dimCD16⁺ cell count.

SE, standard error; CI, confidence interval; sCD163, soluble CD163; IL-6, interleukin-6