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. 2015 Aug 12;4:410. doi: 10.1186/s40064-015-1192-3

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© Zhang et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Roles of monocytes in the Cn pathogenesis. Upon infection, monocytes internalize and kill the Cn. However, Cn could also proliferate in the monocytes and escape the monocytes via the host cell lysis or non-lytic exocytosis. It is speculated that monocyte may also work as Trojan horse in the Cn brain dissemination.