Table 2. Pathological characteristics at diagnosis by tumour location. Data are presented as proportion of individuals within each category.

	UOQ (n = 520)	UIQ (n = 158)	LOQ (n = 143)	LIQ (n = 82)	Central (n = 107)	P value
Stage
I	0.56	0.66	0.53	0.59	0.46	0.003
II	0.33	0.27	0.34	0.30	0.29
III	0.09	0.06	0.11	0.06	0.18
IV	0.02	0.01	0.02	0.05	0.07
ER/HER2 status
ER+/HER2−	0.70	0.76	0.68	0.76	0.71	0.124
ER+/HER2−	0.15	0.08	0.10	0.05	0.07
ER−/HER2+	0.05	0.10	0.07	0.04	0.06
ER−HER2−	0.10	0.06	0.15	0.15	0.16
PR Status
Positive	0.62	0.71	0.67	0.63	0.64	0.248
Negative	0.38	0.29	0.33	0.37	0.36
Lymph node status
Negative	0.64	0.76	0.62	0.66	0.49	<0.001
Positive	0.36	0.24	0.38	0.34	0.51
Tumour Grade
Low	0.29	0.33	0.27	0.26	0.27	0.668
Intermediate	0.37	0.33	0.41	0.43	0.45
High	0.34	0.34	0.32	0.31	0.28
Ki67
<20%	0.58	0.55	0.50	0.42	0.50	0.174
≥20%	0.42	0.45	0.50	0.58	0.50
Tumour Size
T1	0.67	0.71	0.70	0.71	0.52	<0.001
T2	0.28	0.25	0.27	0.29	0.32
T3	0.05	0.04	0.03	0.00	0.16
Angiolymphatic invasion
Absent	0.77	0.78	0.73	0.79	0.68	0.272
Present	0.23	0.22	0.27	0.21	0.32
Dead of Disease
Yes	0.02	0.01	0.05	0.05	0.07	0.011
No	0.98	0.99	0.95	0.95	0.93