Table 1.
Baseline demographics and disease characteristics
| Demographics/characteristics | Primary GCTB (n = 148) |
Recurrent GCTB (n = 74) |
All patientsa
(N = 222) |
|---|---|---|---|
| Sex, n (%) | |||
| Female | 80 (54.1) | 40 (54.0) | 120 (54.1) |
| Male | 68 (45.9) | 34 (46.0) | 102 (45.9) |
| Race/ethnicity, n (%) | |||
| White | 117 (79.1) | 61 (82.4) | 178 (80.2) |
| Asian | 10 (6.8) | 4 (5.4) | 14 (6.3) |
| Hispanic | 10 (6.8) | 3 (4.1) | 13 (5.9) |
| Black | 8 (5.4) | 4 (5.4) | 12 (5.4) |
| Other | 3 (2.0) | 2 (2.7) | 5 (2.3) |
| Age, years, median (Q1, Q3) | 34 (26, 43) | 35 (25, 46) | 34 (25, 44) |
| GCTB presentation status, n (%) | |||
| Primary | 148 | – | 148 (66.7) |
| Recurrent | – | 74 | 74 (33.3) |
| Planned surgery at presentation, n (%)b | |||
| Hemipelvectomy | 10 (6.8) | 0 | 10 (4.5) |
| Amputation | 21 (14.2) | 17 (23.0) | 38 (17.1) |
| Joint/prosthesis replacement | 17 (11.5) | 8 (10.8) | 25 (11.3) |
| Joint resection/fusion | 22 (14.9) | 11 (14.9) | 33 (14.9) |
| En bloc resection | 57 (38.5) | 26 (35.1) | 83 (37.4) |
| En bloc excision | 4 (2.7) | 4 (5.4) | 8 (3.6) |
| Marginal excision | 1 (0.7) | 0 | 1 (<1.0) |
| Curettage | 9 (6.1) | 8 (10.8) | 17 (7.7) |
| Other | 7 (4.7) | 0 | 7 (3.2) |
GCTB giant cell tumor of bone, Q1, Q3 quartile 1, quartile 3
aPatients evaluable for surgical downstaging
bPercentages may not add up to 100 due to rounding