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. Author manuscript; available in PMC: 2016 Jan 16.
Published in final edited form as: Nature. 2015 Jul 8;523(7560):361–365. doi: 10.1038/nature14613

Extended Data Figure 7. Mcm1 sites do not compensate for the loss of a2.

Extended Data Figure 7

a, The presence of the Mcm1 binding site is unchanged across the Candida, Kluyveromyces, and Saccharomyces clades 22,24. asgs were scored for the strength of the Mcm1 binding site in their upstream regulatory regions. The enrichment of the strength of the Mcm1 site in the asgs in each species is shown in the bottom row. b, A construct with increased Mcm1 binding site strength was tested for its ability to compensate for the deletion of a2. Shown is the mean fluorescence of three independent genetic isolates +/− s.d.