Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Duration of crying
Systematic review	Breastfed infants (2–16 weeks) with colic Data from 1 RCT	Reduction in crying (minutes/day) 21 days with Lactobacillus reuteri with placebo Absolute results not reported	Median difference –55.00 95% CI –102.00 to –8.00	Effect size not calculated	L reuteri
Systematic review	Breastfed infants (<3 months) with colic Data from 1 RCT	Reduction in crying (minutes/day) 21 days with L reuteri with placebo Absolute results not reported	Median difference –53.00 95% CI –71.99 to –34.01	Effect size not calculated	L reuteri