Table 2. Univariate linear regression analysis of the 19 SHG morphological features (F1 to F19) and ISHAK fibrosis scores.

No.	Feature abbr.	Feature full name	All P value	Training cohort P value	Verification cohort P value
F1	Cpa	Collagen percentage of area	<0.0001	<0.0001	0.0022
F2	Agg	Aggregated collagen percentage of area	<0.0001	<0.0001	0.0020
F3	Dis	Distributed collagen percentage of area	0.2401	0.3254	0.5274
F4	NoStr	Number of collagen strings	<0.0001	<0.0001	<0.0001
F5	NoShortStr	Number of short collagen strings	<0.0001	<0.0001	<0.0001
F6	NoLongStr	Number of long collagen strings	<0.0001	<0.0001	<0.0001
F7	NoThinStr	Number of thin collagen strings	0.0001	0.0004	0.0372
F8	NoThickStr	Number of thick collagen strings	<0.0001	<0.0001	<0.0001
F9	StrArea	Total string area	<0.0001	<0.0001	0.0051
F10	StrLength	Total string length	<0.0001	<0.0001	<0.0001
F11	StrWidth	Total string width	<0.0001	<0.0001	<0.0001
F12	StrPerimeter	Total string perimeter	<0.0001	<0.0001	<0.0001
F13	NoXlink	Total number of crosslinks	<0.0001	0.0033	0.0004
F14	NoShortStr/NoStr	Ratio between the number of short strings and the total number of strings	0.0011	<0.0001	0.2511
F15	NoLongStr/NoStr	Ratio between the number of long strings and the total number of strings	0.0011	<0.0001	0.2511
F16	NoShortStr/NoLongStr	Ratio between the number of short strings and the number of long strings	0.0002	<0.0001	0.1689
F17	NoThinStr/NoStr	Ratio between the number of thin strings and the total number of strings	0.1276	0.8378	0.1008
F18	NoThickStr/NoStr	Ratio between the number of thick strings and the total number of strings	0.1276	0.8378	0.1008
F19	NoThinStr/NoThickStr	Ratio between the number of thin strings and the number of thick strings	0.0312	0.6115	0.0343