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Effects of clioquinol on ZIP1-deficient PC-3 cells. A. Shows increased zinc accumulation in the presence of clioquinol. B. Shows inhibition of cell proliferation in the presence of CQ+Zn. C. Shows increased phosphorylation of JNK in the presence of CQ+Zn. Cells were exposed to 5 uM CQ treatment for 16 hours. A and C treated with 5 uM Zn.
