Figure 7. DNA-PKcs inhibition modulates expression of pro-metastatic factors in primary human disease.

(A) Schematic of explant assay, adapted from (Schiewer et al., 2012). (B) Representative images of explant tissues treated with control or 1μM NU7441 and stained with hematoxylin & eosin. (C) Explant tissues were harvested on day 6 for qPCR analysis with indicated transcripts set relative to GAPDH. Data are reported as mean +/− SD. *p<0.05.