Table 2.
Activity limitation predictors. Multiple logistic regression models of the effect of clinical measures on the risk of elevated HAQ score among individuals with SLE
| 95 % CI for Odds Ratio | R2 | Predictive ability | |||||||
|---|---|---|---|---|---|---|---|---|---|
| B (SE) | P | LL | OR | UL | H&L | C&S | Sens. | Spec. | |
| Phenotypes | 0.04 | 0.05 | 1 | 0 | |||||
| Constant | 0.947 (0.231) | ||||||||
| Hematologic | −0.926 (0.306) | 0.002 | 0.217 | 0.396 | 0.722 | ||||
| Background variables | 0.07 | 0.09 | 0.79 | 0.45 | |||||
| Constant | −1.49 | ||||||||
| Age | 0.037 (0.009) | <0.001 | 1.019 | 1.038 | 1.057 | ||||
| Disease variables | 0.06 | 0.08 | 0.66 | 0.60 | |||||
| Constant | −0.006 (0.191) | ||||||||
| SDI | 0.375 (0.108) | <0.001 | 1.178 | 1.455 | 1.798 | ||||
| Self-reported measures | 0.26 | 0.29 | 0.84 | 0.76 | |||||
| Constant | 1.891 (1.318) | ||||||||
| EQ5D | −3.276 (1.502) | 0.029 | 0.002 | 0.038 | 0.717 | ||||
| Well-being | 0.043 (0.014) | 0.001 | 1.017 | 1.044 | 1.072 | ||||
| Overall | 0.41 | 0.41 | 0.87 | 0.69 | |||||
| Constant | 0.817 (1.434) | ||||||||
| Age | 0.031 (0.016) | 0.050 | 0.941 | 0.970 | 1.000 | ||||
| SDI | 0.432 (0.194) | .0026 | 1.053 | 1.541 | 2.256 | ||||
| EQ5D | −3.350 (1.502) | 0.026 | 0.002 | 0.035 | 0.666 | ||||
| Well-being | 0.048 (0.014) | <0.001 | 1.020 | 1.049 | 1.078 | ||||
| Hematologic | −1.709 (0.532) | 0.001 | 0.064 | 0.181 | 0.513 | ||||
LL = lower limit; UL = upper limit; H&L = Hosmer & Lemeshow; C&S = Cox & Snell; Sens. = sensitivity; Spec. = specificity; SDI = Systemic Lupus International Collaborative Clinics/ACR damage index; EQ5D = EuroQol–5D