Table 2.

Effect of the dietary interventions in the first period on rectal biology (Mean values with their standard errors; percentages)

	HRM group (n 10)	HRM+HAMSB group (n 13)
	Baseline	Week 4			Baseline	Week 4
	Mean	sem	Mean	sem	Increment	Change (%)	Mean	sem	Mean	sem	Increment	Change (%)	P †
O6MeG load (staining intensity)	60·8	2·3	77·4**	5·8	16·6	21·4	59·8	3·2	67·5	2·3	7·7	11·4	0·14
PCNA (positive cells/crypt)	6·2	0·3	9·9***	1·0	+3·8	38	6·6	0·3	8·6*	0·7	+2·0	23	0·05‡

HRM, high red meat; HAMSB, butyrylated high-amylose maize starch; O⁶MeG, O⁶-methyl-2-deoxyguanosine; PCNA, proliferating cell nuclear antigen.

Mean value was significantly different from that at baseline: * P< 0·05, ** P< 0·01, *** P< 0·001 (linear mixed-effects model).

^† P value was obtained for treatment difference at week 4 (linear mixed-effects model).

^‡ P< 0·05.