Table 1.
Basic characteristics and clinical findings
| Commensal oropharyngeal flora VAP | Reference population | P value | |
|---|---|---|---|
| N = 23 | N = 899 | ||
| Age, mean (SD) | 55 (16) | ||
| Male (%) | 16 (70 %) | 557 (62 %) | .52 |
| Medical history (%) | |||
| Cardiac | 12 (52 %) | ||
| Pulmonary | 7 (30 %) | ||
| Oncologic | 7 (30 %) | ||
| Immunocompromised | 2 (9 %) | 98 (11 %) | .85 |
| Indication for ICU admission (%) | |||
| Surgical | 13 (57 %) | 267 (30 %) | .01 |
| Non-surgical | 10 (43 %) | 632 (70 %) | .01 |
| ICU admission scores (SD) n = 21 | |||
| APACHE-II score | 19.8 (9.9) | 19.1 (8.4) | .75 |
| Predicted mortality | 31 % (26) | 34 % (26) | .60 |
| SOFA score | 8.1 (3.3) | ||
| Characteristics at the day of diagnosis (SD) | |||
| SOFA score | 6.9 (3.7) | ||
| Body temperature (°C) | 38.3 (1.1) | ||
| WBC count (109/L) | 14.3 (8.4) | ||
| CRP (mg/L) | 180 (108) | ||
| CPIS | 6.4 (2.1) | ||
| Median days on MV (IQR) | 8 (4–19) | ||
| Number of BAL fluid cells | 6.9*105 (1.7*105) | ||
| of which PMNs | 60 % (35) | ||
| of which containing ICOs | 5.1 (6.5) | ||
| Outcome | |||
| ICU mortality | 9 (39 %) | 234 (26 %) | .16 |
| SMR (SD) | 1.26 (0.42) | 0.77 (0.04) | .14 |
| 28-day mortality | 3 (13 %) | ||
| 60-day mortality | 6 (26 %) | ||
| Median hospital LOS (IQR) | 63 (50–146) | 23.7 (=mean) | .001 |
| Median ICU LOS (IQR) | 33 (13–62) | 5.7 (=mean) | .000 |
| Median days on MV (IQR) | 34 (17–67) | ||
| Median hospital LOS after diagnosis (IQR) | 22 (10–59) | ||
| Median ICU LOS after diagnosis (IQR) | 13 (7–55) |
If no number is provided, this information was not available in the Netherlands intensive care evaluation registry. APACHE-II score could not be calculated in 2 patients due to incomplete admission data