Table 3.

Correlation between p53 expression and clinicopathological parameters of gastric cancer

Clinicopathological parameters	Total (n=145)	p53 expression		p-value
		Positive (n=52)	Negative (n=93)
Age (years)
< 60	67	25	42	0.736
≥ 60	78	27	51
Sex
Male	99	37	62	0.578
Female	46	15	31
Tumor size (cm)
< 5.0	66	25	41	0.594
≥ 5.0	79	27	52
Lauren Classification*
Intestinal	70	27	43	0.280
Diffuse	42	11	31
Mixed	33	14	19
Differentiation grade*
WD	24	9	15	0.721
MD	45	18	27
PD	76	25	51
TNM stage
I	52	17	35	0.280
II	21	6	15
III	47	22	25
IV	25	7	18
Depth of tumor invasion (T)
T1	24	3	21	0.147
T2	32	18	14
T3	75	25	50
T4	14	6	8
Lymph node metastasis (N)
N0	70	23	47	0.456
N1–3	75	29	46
Distant metastasis (M)
M0	125	46	79	0.556
M1	20	6	14

^*WD, well differentiated; MD, moderately differentiated; PD, poorly differentiated adenocarcinoma