Table 4.
HLA DR, DQ and DP allelelic frequency(%) in controls and SLE patients divided according to their clinical manifestations and age of onset (number of alleles in parentheses)
| HLA | SLE N=56 | Contro N=59 | Renal N=38 | Arthritis N=24 | Malar rash n=38 | Photo n=28 | Ulcers n=20 | Alopecia n=36 | Onset<30 yrs n=20 |
|---|---|---|---|---|---|---|---|---|---|
| DR | |||||||||
| 2 | 86 | 61 | 90** | 88 | 82 | 89 | 90 | 89 | 75 |
| 3 | 14 | 15 | 13 | 13 | 13 | 7 | 15 | 14 | 20 |
| 4 | 11 | 12 | 11 | 4 | 11 | 14 | 15 | 11 | 15 |
| 5 | 34 | 48 | 34 | 42 | 37 | 39 | 45 | 28 | 30 |
| 8 | 2 | 0 | 3 | 33** | 0 | 0 | 0 | 0 | 0 |
| 9 | 5 | 9 | 5 | 8 | 0 | 0 | 5 | 6 | 5 |
| DQA1 | |||||||||
| 0601 | 13 | 27 | 13 | 4 | 53 | 11 | 20 | 11 | 25 |
| 0501 | 16 | 9 | 8 | 13 | 16 | 14 | 25 | 11 | 5 |
| 0103 | 7 | 2 | 11 | 4 | 16 | 4 | 10 | 6 | 5 |
| DQB1 | |||||||||
| 0501 | 48 | 17 | 58* | 67* | 47* | 36 | 40 | 56* | 65 |
| 0502 | 9 | 17 | 5 | 8 | 8 | 11 | 15 | 6 | 0 |
| 0503 | 18 | 39 | 13 | 25 | 24 | 32 | 20 | 11 | 25 |
| 0601 | 36 | 9 | 37 | 17 | 29 | 32 | 40* | 42 | 25 |
| 0301 | 14 | 34 | 13 | 21 | 16 | 14 | 20 | 17 | 10 |
| 0201 | 43 | 24 | 50 | 25 | 45 | 43 | 50 | 42 | 5 |
| DPB1 | |||||||||
| 0101 | 16 | 9 | 24 | 21 | 16 | 20 | 5 | 17 | 20 |
| 0201 | 11 | 17 | 8 | 13 | 8 | 7 | 10 | 14 | 10 |
| 0301 | 9 | 14 | 13 | 13 | 8 | 11 | 15 | 8 | 20 |
| 0901 | 34 | 4 | 37 | 38 | 40 | 36 | 25 | 25 | 25 |
*:
pc significant vs controls
**:
pc significant vs antibody negative patients