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Electron micrograph of the liver in a patient with alcoholic fatty liver. A hepatic stellate cell (HSC) was conspicuous with its abundant and well-developed rough endoplasmic reticulum (arrows). The space of Disse contained many collagen bundles (C) (grade 2+). The smooth endoplasmic reticulum of hepatocytes was hypertrophied. H; hepatocyte, F; fat vacuole (×10,000).
