Table 1.

Development of the catalytic aminofluorination reaction^[a]

Entry	Catalyst	Solvent	Yield [%][b]
1	[Cu(MeCN)4]BF4	CH2Cl2	65
2	[Pd(MeCN)4](BF4)2	CH2Cl2	50
3	[Ag(MeCN)4]BF4	CH2Cl2	46
4	AgBF4	CH2Cl2	58
5	CuCl	CH2Cl2	0
6	Zn(BF4)2⋅x H2O	CH2Cl2	75
7	Zn(BF4)2⋅x H2O	THF	40
8	Zn(BF4)2⋅x H2O	PhCH3	63
9	Zn(BF4)2⋅x H2O	CH3CN	<5
10[c]	Zn(BF4)2⋅x H2O	CH2Cl2	0
11	–	CH2Cl2	0

[a] Reaction conditions: 0.1 mmol of 2 a, Zn(BF₄)₂⋅XH₂O (5 mol %) and 1 (1.1 equiv) was reacted in CH₂Cl₂ (0.5 mL) at RT. [b] Yield of the isolated product. [c] Fluoroiodine 1 was not added. THF=tetrahydrofuran.