Figure 4.

A:15 channels of M1 (blue) and 12 channels of M2 (black) recorded from P1 during a clinical seizure, the inset shows a schematic of the implanted grid along with M1 and M2 with the black asterisk denoting the location of the SOZ macro-electrode contact with respect to M1; B: The 4–50 Hz (green) and the 70–110 Hz (blue) flows in the macro-channels surrounding M1 and M2. The thickness of the arrows is proportional to the number of times a particular direction of flow occurred in the entire interval considered as in D; C: time evolution and histogram of micro-electrode contact emanating the maximum outflow within grids M1 and M2 respectively. The channel having maximum outflow for the highest number of times over the entire seizure duration is marked in black and red for M1 and M2 respectively in the schematic in A ; D:Top 4 percentile of propagation in the 70–90 Hz frequency band across M1 (bottom) and M2 (top) along with the strongest flow across the neighboring macro-electrode contacts in the 4–50 Hz (green) and the 70–110 Hz (blue) frequency bands. Each square element corresponds to a time interval of 2 s and consecutive squares are separated by 0.5 s. The temporal evolution is from left to right. The 32 patterns shown thus correspond to a total duration of 16 s as shown in A.