Table 2.
APAP | APAP + EGCG | |
---|---|---|
Plasma (us/ml) | ||
APAP | 371.2± 126.2 | 387.5± 62.9 |
APAP-glucuronate | 135.9± 10.0 | 83.5± 24.9* |
APAP-sulfate | 42.2± 3.4 | 36.9± 3.0* |
APAP-glutathione | 18.3± 2.2 | 10.7± 2.9* |
Liver (us/s liver) | ||
APAP | 116.4± 58.1 | 45.9± 18.6* |
APAP-glucuronate | 55.5± 3.5 | 32.2± 12.4* |
APAP-sulfate | 11.0± 0.8 | 10.3± 0.6 |
APAP-glutathione | 58.2± 28.4 | 17.6± 4.1* |
APAP protein adducts | 40.5± 3.1 | 39.4± 2.7 |
Results are expressed as the mean± S.D. of six rats in each dietary group. The amount of EGCG in the diet was 0.54 % (w/w).
*Significantly different from APAP group, P < 0.05.