Table 3.
Results obtained from histologic scoring and p53 immunohistochemical staining.
Patient | PMN cell infiltration | Hyperemia | Fibrin deposition | Mononuclear cell infiltration | Synovial cell proliferation | Fibrosis | p53* |
---|---|---|---|---|---|---|---|
RA | |||||||
1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
2 | 1 | 0 | 1 | 1 | 0 | 1 | 2+ |
3 | 0 | 3 | 1 | 0 | 0 | 0 | 0 |
4 | 2 | 1 | 2 | 3 | 0 | 2 | 2+ |
5 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
6 | 2 | 1 | 0 | 2 | 1 | 2 | 0 |
7 | 1 | 2 | 0 | 2 | 0 | 2 | 0 |
8 | 0 | 1 | 1 | 1 | 0 | 3 | 0 |
9 | 0 | 1 | 1 | 1 | 0 | 1 | 1 + |
mean(SEM) | 0.7(0.3) | 1.1(0.3) | 0.8(0.2) | 1.2(0.3) | 0.1(0.1) | 1.2(0.4) | 0.6(0.3) |
OA | |||||||
1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
2 | 2 | 1 | 3 | 1 | 0 | 0 | 1+ |
3 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
5 | 2 | 1 | 2 | 1 | 0 | 0 | 1+ |
mean(SEM) | 0.8(0.5) | 0.8(0.2) | 1.0(0.6) | 0.4(0.2) | 0.0(0.0) | 0.0(0.0) | 0.4(0.2) |
p-value | 0.79 | 0.71 | 1.00 | 0.32 | 1.00 | 0.18 | 0.41 |
RA: Rheumatoid arthritis, OA: Osteoarthritis, PMN: Polymorphonuclear
0, no staining; 1+, rare positive cells or trace staining; 2+, scattered clusters of positive cells; 3+, moderated staining in a specific region; 4+, extensive staining throught a region