Fig. 3.

Temporal changes of activities of CDKs in atria during the fetal and adult periods. Autoradiographic analyses were performed for activities of CDKs from immunoprecipitated complexes. pRb was used as substrate for CDK4 or CDK6 activities. Histone H1 was used as substrate for CDK2 and cdc2 activities. The detailed protocol is described in the MATERIALS AND METHODS section. The legends of ages are the same as shown in Fig. 1. Results were similar to three separate experiments.