Table 1.
Clinico-biochemical Profiles of Diabetic Patients Studied (mean±SD)
| Profiles | Total diabetics (n=49) | Insulin-treated group (n=17) | Sulfonylurea-treated group (n=10) | Biguanide-treated group (n=22) |
|---|---|---|---|---|
| Men: Women | 23:26 | 10:7 | 7:3 | 6:16 |
| Age (year) | 51.2±14.9 | 50.6±30.7 | 49.9±16.6 | 52.2±13.2 |
| Duration (year) | 7.8±6.1 | 9.2±6.2 | 8.4±7.6 | 7.5±5.5 |
| BMI (kg/m2) | 23.2±3.4 | 20.8±1.7 | 21.3±3.6 | 26.0±2.3≠ |
| HbAlc (%) | 8.2±1.5 | 8.4±1.9 | 7.4±1.2 | 8.4±1.1 |
| Blood sugar (mg/dl) | ||||
| Fasting 1* | 160.9±69.5 | 175.0±90.8 | 156.1±59.2 | 152.2±57.8 |
| Fasting 2+ | 156.0±53.6 | 153.8±69.3 | 150.0±83.4 | 151.5±27.9 |
| C-peptide (ng/ml) | ||||
| Basal | 2.01±1.62 | 1.77±1.87 | 1.67±1.04 | 2.56±1.46 |
| Serum lipid (mg/dl) | ||||
| Total cholesterol | 187.3±65.3 | 171.5±72.7 | 173.6±52.1 | 204.7±62.7 |
| HDL cholesterol | 45.2±10.9 | 43.1±9.9 | 45.3±17.1 | 46.6±9.2 |
| LDL cholesterol | 114.6±49.5 | 100.4±65.4 | 103.1±35.7 | 128.5±37.7 |
| Triglyceride | 168.8±78.2 | 142.9±73.9 | 172.7±117.4 | 186.5±62.1 |
| Proteinuria (mg/24 hr) | 239.5±555.4 | 417.4±803.21 | 169.2±164.1 | 134.1±228.7 |
| Follow-up perio (day) | 36.1±16.7 | 33.8±18.5 | 35.7±16.6 | 38.0±15.4 |
*
Fasting blood sugar (FBS) before treatment,
+
FBS after treatment
≠
p<0.05 compared with insulin and sulfonylurea-treated groups