Table 3.
Reproductive characteristics of Saudi breast cancer cases and controls
| Parameter | Cases number (%) | Controls number (%) | OR 95% confidence intervals | P-values |
|---|---|---|---|---|
| Menopausal Status | < 0.0001 | |||
| Pre-menopause | 264 (49.7) | 484 (76.5) | 1 | |
| Postmenopausal | 267 (50.3) | 149 (23.5) | 3.29 (2.56 – 4.22) | |
| Age at menarche (years) | 0.0767 | |||
| < 13 | 379 (70.9) | 422 (66.1) | 1 | |
| ≥ 13 | 155 (29.1) | 216 (33.9) | 0.80 (0.62 – 1.03) | |
| Breastfeeding | 0.8739 | |||
| No | 38 (8.0) | 38 (8.0) | 1 | |
| Yes | 440 (92.1) | 457 (92.0) | 0.96 (0.60 – 1.54) | |
| Use of hormonal replacement therapy | < 0.0001 | |||
| No | 191 (35.9) | 329 (52.3) | 1 | |
| Yes | 341 (64.1) | 300 (47.7) | 1.96 (1.55 – 2.48) | |
| Age at menopause (years) | 0.0001 | |||
| < 45 | 67 (30.0) | 7 (8.0) | 1 | |
| ≥ 45 | 156 (70.0) | 81 (92) | 0.20 (0.09 – 0.46) |
Median values were used as cutoff point for age at menopause and age at menarche.
Abbreviation: OR odds ratio.