Table 3.
Mean concentrations of biomarkers of exposure in studied groups (data are reported as mean ± SE and range in brackets)
| Study group
|
||||||||
|---|---|---|---|---|---|---|---|---|
| n | Unexposed Controls | n | Organic Farmers | n | Pesticide workers | p-value | p-value adjusted for age and last exposure | |
| PYR (μg/mmol creat) | 60 | 0.13 ± 0.04 (nd – 1.35) | 36 | 0.06 ± 0.05 (nd – 1.92) | 85 | 0.08 ± 0.03 (nd – 1.66) | 0.137 | 0.185 |
|
| ||||||||
| OP/CRB (μg/mmol creat) | 60 | 1.54 ± 0.23a (nd – 11.73) | 36 | 1.86 ± 0.30a,b (nd – 9.61) | 85 | 2.23 ± 0.19b (nd – 8.22) | 0.030 | 0.002 |
|
| ||||||||
| THIO (μmol/mmol creat) | 60 | 51.83 ± 3.28 (20.95 – 187.46) | 35 | 62.56 ± 5.60 (23.49 – 217.95) | 85 | 54.33 ± 3.16 (20.08 – 229.41) | 0.111 | 0.003 |
|
| ||||||||
| BChEc (U/L) | ||||||||
| Class 1 | 41 | 6425.44±224.15 (3347 – 9083) | 29 | 6245.62±191.41 (4408 – 8647) | 56 | 7063.66±202.31 (4142 – 9707) | 0.943 | 0.059 |
| Class 2 | 7 | 5965.57±642.23 (3902 – 8966) | 6 | 5803.83±661.51 (3964 – 7890) | 21 | 6240.43±289.27 (3539 – 9044) | ||
| Class 3 | 13 | 6553.31±443.78 (4944 – 10192) | 1 | 7074 (7074 – 7074) | 7 | 6950.86±466.79 (5485 – 9050) | ||
a, b
Homogeneous groups according to multiple comparison Tukey’s test;
c
classes established according to age and gender; nd – not detected; creat – creatinine.