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. 2015 Aug 5;9:4291–4302. doi: 10.2147/DDDT.S86300

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© 2015 Ballester et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Mean natriuresis efficiency (mmol/μg) following oral administration of 10 mg torasemide-IR (Δ), 10 mg torasemide-PR (○), and 40 mg furosemide-IR (•) plotted against the midpoint (hours) of the entire collection interval.

Notes: Data points are time-course (expressed as midpoint of the entire collected interval) of the mean natriuresis efficiency, calculated as the ratio between drug-induced natriuresis and drug recovered in urine over 24 hours.

Abbreviations: IR, immediate release; PR, prolonged release.