Table 6.
Predicted plasma CL and Vss values using different methods
Parameter | Method | Value |
---|---|---|
CL (L/h/kg) | Allometric scaling (BrW) | 0.19 |
Liver blood flow method | 0.23 | |
Single species scaling | 0.23 | |
Vss (L/kg) | Allometric scaling (BrW) | 1.70 |
Oie-Tozer | 5.53 |
Abbreviation: CL, clearance.