Fig. 6.

Alcoholic white matter degeneration. a Periventricular frontal white matter from the anterior frontal region of a non-alcoholic middle-aged man. Other regions of brain showed similar degrees of myelin staining. b–d Cerebral white matter degeneration is present in the brain of an alcoholic middle-aged man with dementia. White matter from the b anterior frontal, c periventricular frontal, and d periventricular region at the level of the hypothalamus with variable degrees of myelin pallor, vacuolation, and gliosis relative to normal