Table 1.
Clinical and outcome characteristics
| Perfusion study | Normal (n = 10) | FGR (n = 10) | P |
|---|---|---|---|
| Maternal age (years) | 29.5 [25.75–33] | 29 [22.75–34.75] | 0.91 |
| BMI | 22.9 [22.4–27.5] | 25 [22.75–27.50] | 0.649 |
| Parity | 1 [0–1.25] | 1 [0.75–2.25] | 0.362 |
| Gestation (weeks) | 39.2 [38.9–40.6] | 37.5 [35.63–39.18] | < 0.05* |
| Delivery (V/CS)† | 2/8 | 4/6 | N.A |
| PI‡ | 0.88 [0.80–0.93] | 1.09 [0.908–1.783] | < 0.05* |
| RI‡ | 0.565 [0.528–0.603] | 0.670 [0.612–0.800] | < 0.005*** |
| Birth weight (g) | 3517 [3359–3704] | 2189 [1518–2483] | < 0.001*** |
| IBR (centile) | 61 [22–84.3] | 1 [0–2.5] | < 0.001*** |
| Offspring sex# | 6M, 4F | 4M, 6F | N.A |
| Placenta disc weight (g) | 499 [438–642] | 279 [225–372] | < 0.001*** |
| Perfused lobule weight (g) | 49.75 [42–76] | 43.75 [24–72] | 0.623 |
| HPAEC study | Normal (n = 7) | FGR (n = 7) | P |
|---|---|---|---|
| Maternal age (years) | 26 [23–29] | 26 [23–33] | 0.364 |
| BMI | 25 [23–26] | 23 [21–25] | 0.174 |
| Parity | 1 [0–2] | 1[0–2] | 0.947 |
| Gestation (weeks) | 39 [38.1–39.0] | 38 [36–39.4] | 0.653 |
| Delivery (V/CS)† | 0/7 | 6/1 | N.A. |
| Birth weight (g) | 3816 [3560–3860] | 2440 [1980–2778] | < 0.001*** |
| IBR (centile) | 83 [75–88] | 3 [1–5] | < 0.005** |
| Offspring sex# | 3M, 4F | 4M, 3F | N.A. |
| Placenta disc weight (g) | 588 [532–660] | 432 [294–455] | < 0.005** |
Values are shown as median [interquartile range];
statistical analysis was performed using a Mann–Whitney U test.
BMI, body mass index; IBR, individualised birth weight ratio.
†
Vaginal (V)/Caesarean section (CS).
‡
Pulsitility index (PI) and resistance index (RI) values represent n = 8 for the FGR group since there was absent end diastolic flow in two of the pregnancies.
#
Male (M), female (F).