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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: J Stroke Cerebrovasc Dis. 2015 May 6;24(8):1817–1822. doi: 10.1016/j.jstrokecerebrovasdis.2015.04.018

Table 4.

Effect of COX-2 gene polymorphisms on log-transformed white matter hyperintensity volume in 788 stroke patients from the Boston cohort (adjusted for age, sex, and principal components 1 and 2). The non-cardioembolic (non-CE) cohort had 486 patients.

SNP Cohort Risk Allele Effect estimate Standard error P-value
rs199545927 All A 0.247 0.124 0.047
rs199545927 Non-CE A 0.383 0.160 0.016
rs20417 All C 0.092 0.061 0.131
rs20417 Non-CE C 0.164 0.079 0.037
rs201231411 Non-CE A 0.339 0.149 0.023