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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Med Image Anal. 2015 May 18;24(1):63–76. doi: 10.1016/j.media.2015.05.002

Table 8.

Contrast values between neighboring structures for original, synthetic, and atlas images.

Structure Boundary Contrasts

Struct. Boundaries Original Ψ-CLONE Atlas
Cort CSF–Cort GM 0.594 0.604* 0.625
Cort GM–WM 0.480 0.482 0.489
WM–Lesions 0.279 0.300
WM–Caudate 0.341 0.367* 0.370
WM–Putamen 0.214 0.219 0.240
WM–Thalamus 0.176 0.208* 0.269
WM–Ventricles 0.846 0.863* 0.878
Ventricles–Caudate 0.765 0.784* 0.804
Ventricles–Thalamus 0.814 0.827* 0.834
*

indicates that the contrast in synthetic images higher than the original images (statistically significant using Student's one-tailed T test with p < 0.05).