Table 2.

Baseline Clinical and Imaging Characteristics Associated with Mild and Non-Mild Symptoms in Patients with Proximal, Distal, and No Occlusion on MRA^*

	Proximal			Distal			MRA-Negative
	NIHSS <= 4 (n=4)	NIHSS > 4 (n=26)	p	NIHSS <= 4 (n=11)	NIHSS > 4 (n=25)	p	NIHSS <= 4 (n=20)	NIHSS > 4 (n=5)	p
Age (y)	82[71.5–83.75]	76.5[66.5–86]	1	80[56.5–82]	78[68–83]	0.68	70[60–85]	74.5[60.5–81]	0.89
Sex (Female)	3(75)	10(38.5)	1	6(54.5)	17(68)	0.69	5(25)	3(60)	0.33
Admit NIHSS	1.5[1–2.5]	14.5[10–16.75]	---	3[2.5–3.5]	10[7–14]	---	6[5–7]	1[0.75–3]	---
Baseline PWI (mL)	207.3[171.5–237.3]	203.4[162.9–224.6]	0.98	107.8[55.42–150.7]	129.5[97.64–160.2]	0.34	18.98[17.37–30.67]	12.57[3.23–42.14]	0.87
Baseline DWI (mL)	4.11[1.56–10.43]	7.29[2.94–44.64]	0.36	3.58[2.79–8.15]	32.13[17.48–46.38]	<.001	1.68[1.06–10.48]	1.16[0.39–3.40]	0.27
Baseline MM (mL)	192.7[153.8–232.5]	162.8[146.7–214.3]	0.54	101.1[51.77–142.9]	85.88[65.63–121.9]	0.95	17.3[16.31–17.57]	8.66[1.16–41.1]	1
Onset-Baseline MRI Time (min)	264.3[185–535.5]	123.2[83.52–481.7]	0.46	168[128.4–617.8]	168.6[117.7–326.2]	0.97	279.5[109.9–638.4]	158.8[113.2–508.9]	0.97
Initial Growth Velocity (mL/hr)	0.82[0.40–2.36]	4.67[1.12–11.68]	0.23	1.28[0.25–4.68]	5.94[3.46–15.2]	0.01	0.42[0.07–0.61]	0.36[0.31–1.23]	.536
Hypertension	3(75)	19(73.1)	1	6(54.5)	19(76)	0.37	3(60)	13(65)	1
Diabetes Mellitus	0(0)	7(26.9)	0.58	2(18.2)	4(16)	1	1(20)	3(15)	1
Atrial Fibrillation	1(25)	16(61.54)	0.41	3(27.3)	11(25)	0.56	1(20)	5(25)	1
Hyperlipidemia	1(25)	8(30.77)	1	6(54.5)	17(68)	0.69	0(0)	10(50)	0.13
IV t-PA Treated	1(25)	7(27)	1	3(27)	8(25)	1	2(10)	2(40)	0.34
Lesion Side (Right)	2(50)	13(50)	1	7(63.6)	13(52)	0.78	13(65)	2(40)	0.61

^*Data are expressed as n (%) or median [IQR25–75].