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. Author manuscript; available in PMC: 2016 Dec 15.
Published in final edited form as: Biol Psychiatry. 2015 Feb 11;78(12):848–859. doi: 10.1016/j.biopsych.2015.02.004

Figure 4. Knockdown of Gomafu lncRNA induces anxiety-like behavior.

Figure 4

(A and E) A mild anxiety test performed on Gomafu knockdown animals in an activity monitoring chamber demonstrated that significantly less time was spent in the center of the field (**p<0.01, t=3.922 df=16, n=9 per group). (B, C, D) Gomafu knockdown mice also exibited a significant tendency to travel longer distances outside the center of the field, as well as having an increased ambulatory and stereotypic grooming time compared to control animals (*p<0.05, t=2.523 df=16, n=9 per group; *p<0.05, t=2.158 df=16, n=9 per group and *p<0.05, Mann-Witney U 16, n=9 per group respectively).