Table 1.
Descriptive characteristics, global PiB retention, and behavioral self-report measures
| Demographic and clinical variables | |
| Age, mean (SD), y | 81.2 (8.4) |
| Education, mean (SD), y | 15.4 (2.8) |
| Male sex, n (%) | 47 (51.1 %) |
| Non-white race, n (%) | 9 (9.8 %) |
| APOE*4 carrier, n (%) | 14/80 (15.2 %) |
| GDS, mean (SD) | 3.6 (3.7) |
|
| |
| No. total medications, mean (SD) | 7.5 (3.4) |
|
| |
| Psychotropic medication use, n (%) | 12 (13.5 %) |
|
| |
| Objective cognition measures | |
|
| |
| MMSE, mean (SD) | 28.7 (1.3) |
|
| |
| Modified 24-point R-O figure delayed recall, mean (SD) | 17.4 (3.2) |
|
| |
| Trail Making Test B, s, mean (SD) | 91.9 (40.6) |
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| |
| Animal fluency, no. in 60 s, mean (SD) | 19.4 (4.8) |
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| |
| Digit Symbol, mean (SD) | 46.2 (12.5) |
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| |
| Global SUV-R PiB retention | 1.77 (0.44) |
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| |
| % WMH of total brain volume, mean (SD) | 0.645 (0.704) |
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| |
| Subjective cognition measures | |
| MFQ (measure range 64–448, lower is worse) | 299.7 (38.1) |
| CFQ (measure range 0 – 100, higher is worse) | 34.5 (9.5) |
| SCCS (measure range 0 – 24, higher is worse) | 4.1 (3.4) |
|
| |
| Personality measures | |
| Neuroticism, T score | 41.4 (7.5) |
| Extraversion, T score | 51.5 (9.3) |
| Openness to Experience, T score | 53.1 (7.9) |
| Agreeableness, T score | 55.9 (7.7) |
| Conscientiousness, T score | 43.1 (7.5) |
Abbreviations. GDS = Geriatric Depression Scale; R-O = Rey-Osterrieth; SUV-R= standardized uptake value ratio; PiB= Pittsburgh compound B; WMH=white matter hyperintensities; MFQ = Memory Functioning Questionnaire; CFQ = Cognitive Failures Questionnaire; SCCS = Subjective Cognitive Complaints Scale.
Note. T-score mean = 50; SD = 10.