(A) DTI analysis revealed that whole brain volume (mm3) increased from P80 to P220 (main effect of AGE: F(1,20) = 65.6, p < 0.01) that did not interact with adolescent intermittent ethanol (AIE) treatment. **, p < 0.01. (B) Pearson’s r correlation found that whole brain volumes (mm3) were positively correlated with wet brain weights (g; r = 0.96, n = 24, p < 0.01).