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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Addict Biol. 2015 Feb 11;21(4):939–953. doi: 10.1111/adb.12232

Figure 7. Diffusion tensor imaging reveals that aging and adolescent intermittent ethanol (AIE) affect mean diffusivity (MD) in the adult brain.

Figure 7

(A) Cerebellar MD declined from postnatal day (P)80 to P220 (main effect of AGE: F(1,20) = 5.8, p < 0.05), and was significantly decreased by AIE treatment, relative to CONs (main effect of TREATMENT: F(1,20) = 8.6, p < 0.01). (B) Adolescent intermittent ethanol treatment significantly reduced MD in the corpus callosum, relative to CONs (main effect of TREATMENT: F(1,20) = 6.1, p < 0.05). (C) Hippocampal MD was unaffected by aging or AIE treatment. (D) Neocortex AD was unaffected by aging or AIE treatment. Depicted are means ± S.E.M. * p < 0.05, ** p < 0.01.