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. 2015 Jun 15;7(6):1045–1057.

Table 1.

Effects of BK preconditioning on physiological parameters, cardiac function and infarct size at 10 days following myocardial infarction

Variable Sham Con EPCs BK PC BK PC/HOE BK PC/LY
HW/BW (mg/g) 5.79±0.82 7.85±0.52 7.21±0.75* 6.57±0.71*,# 7.19±0.83 7.23±0.92
LVEF (%) 78.72±5.24 27.89±3.32 38.21±4.32* 48.63±4.91*,# 36.97±4.11 37.12±2.66
LVFS (%) 48.19±4.42 12.59±1.46 17.22±1.85* 27.57±2.81*,# 17.42±2.11 18.39±1.95
LVIDd (mm) 3.32±0.42 5.32±0.53 4.48±0.63* 3.48±0.35*,# 4.42±0.22 4.51±0.83
LVIDs (mm) 1.72±0.15 4.65±0.52 3.71±0.41* 2.52±0.35*,# 3.65±0.31 3.68±0.47
Infarct size (%) 0 49.21±5.12 39.05±3.74* 28.03±3.21*,# 37.64±4.43 38.78±5.18

Values are expressed as mean ± SEM. HW, heart weight; BW, body weight. LVEF, left ventricular ejection fraction; LVFS, left ventricular fractional shortening; LVIDd, left ventricular internal diameter at end-diastole; LVIDs, left ventricular internal diameter at end-systole. BK, bradykinin; PC, preconditioning; HOE, HOE140; LY, LY294002.

*

P < 0.01 vs. Con group;

#

P < 0.01 vs. EPCs group.

n = 5 for each group.