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. 2015 Aug 4;6:7844. doi: 10.1038/ncomms8844

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Transmission electron microscopy showed specialized contacts (arrows) between OPC processes (OPC) and axon varicosities (Ax) containing intracellular vesicles (small arrows in a) and mitochondrion, but no synapses were detected. Three examples for each condition are shown. Insets (right column) show these junctions at higher magnification. Such contacts were evident in cultures stimulated for 9 s at 10 Hz every 5 min for 10 h (Stim) before plating OPCs, and unstimulated cultures (b), but such contacts were not found in stimulated cultures treated with BoNT/A before adding OPCs (c). Scale bar, 1 μm.