Figure 1.

(a) Western blot and (b–f) densitometric analysis (arbitrary units normalized on the expression of the housekeeping protein β-actin) showing the effect of 7 days of intrahippocampal injection of pentamidine (0.05–5 μg/mL/day) on GFAP (b), iNOS (c), p-p38 MAPK (d), COX-2 (e), and RAGE (f) expression in Aβ-injected mice. Results are expressed as mean ± SEM of n = 5 experiments performed in triplicate. ^∗∗∗ P < 0.001 versus vehicle-treated mice; °P < 0.05, °°P < 0.01 and °°°P < 0.001 versus Aβ-treated mice.