Figure 2. Crystallographic structure of dimeric NUDT15.
(a) Top view of Nudt15 dimer (chain A in cyan and chain B in orange) ribbon representation with Mg coordination, and the NUDIX box highlighted in magenta. (b) Surface representation of NUDT15 dimer looking into the putative binding pocket. (c) Side view of NUDT15 dimer. (d) Four Mg ions in coordination (green spheres) with multiple waters (red spheres), E63, E67 and carbonyl oxygen of G47 residues in the NUDIX box (magenta).